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Environmental Allergens Trigger Type 2 Inflammation Through Ripoptosome Activation

Environmental allergens including fungi, insects and mites trigger type 2 immunity; however, the innate sensing mechanisms and initial signaling events remain unclear. Herein, we demonstrate that allergens trigger RIPK1-caspase 8 ripoptosome activation in epithelial cells. The active caspase 8 subse...

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Detalles Bibliográficos
Autores principales:	Brusilovsky, Michael, Rochman, Mark, Rochman, Yrina, Caldwell, Julie M., Mack, Lydia E., Felton, Jennifer M., Habel, Jeff E., Porollo, Aleksey, Pasare, Chandrashekhar, Rothenberg, Marc E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487942/ https://www.ncbi.nlm.nih.gov/pubmed/34531562 http://dx.doi.org/10.1038/s41590-021-01011-2

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