Transposon-triggered innate immune response confers cancer resistance to the blind mole rat

Blind mole rats (BMRs) are small rodents, characterized by exceptionally long lifespan (> 21 years) and resistance to both spontaneous and induced tumorigenesis. Here we report that cancer resistance in the BMR is mediated by retrotransposable elements (RTEs). BMR cells and tissues express very l...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Oreskovic, Ena, Zhang, Quanwei, Lu, Quan, Gilman, Abbey, Lin, Yifei S., He, Junyue, Zheng, Zhizhong, Lu, J. Yuyang, Lee, Jina, Ke, Zhonghe, Ablaeva, Julia, Sweet, Matthew, Horvath, Steve, Zhang, Zhengdong, Nevo, Eviatar, Seluanov, Andrei, Gorbunova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488014/
https://www.ncbi.nlm.nih.gov/pubmed/34556881
http://dx.doi.org/10.1038/s41590-021-01027-8

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