Cargando…

Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1–Dependent Myeloid Cells

Immune cells regulate tumor growth by mirroring their function as tissue repair organizers in normal tissues. To understand the different facets of immune–tumor collaboration through genetics, spatial transcriptomics, and immunologic manipulation with noninvasive, longitudinal imaging, we generated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Van de Velde, Lee-Ann, Allen, E. Kaitlynn, Crawford, Jeremy Chase, Wilson, Taylor L., Guy, Clifford S., Russier, Marion, Zeitler, Leonie, Bahrami, Armita, Finkelstein, David, Pelletier, Stephane, Schultz-Cherry, Stacey, Thomas, Paul G., Murray, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Tumor Biology and Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488023/ https://www.ncbi.nlm.nih.gov/pubmed/34301764 http://dx.doi.org/10.1158/0008-5472.CAN-21-0691

Ejemplares similares

Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells
por: Weis-Banke, Stine Emilie, et al.
Publicado: (2022)

THU481 Glucocorticoid Regeneration By Tumor Cells Promotes Growth By Enhancing Regulatory T Cell Immunosuppression
por: Taves, Matthew D, et al.
Publicado: (2023)

SUN-311 Pervasive Hypoglycemia in the Unconventional Face of Ovarian Cancer
por: Moussa, Ray, et al.
Publicado: (2019)

THU554 Unconventional Estrogen Receptor Antagonists Reveal Cryptic Therapeutic Anti-breast Cancer Transcriptional Pathways
por: Hancock, Govinda, et al.
Publicado: (2023)

Epigenetic modulation of neuroblastoma enhances T cell and NK cell immunogenicity by inducing a tumor-cell lineage switch
por: Cornel, Annelisa M, et al.
Publicado: (2022)

Identification of neuroblastoma cell lines with uncommon TAZ(+)/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells
por: Canzonetta, Claudia, et al.
Publicado: (2021)

Giant Cell Tumor (GCT) of Capitate
por: Narayana Gowda, BS, et al.
Publicado: (2012)

Development and characterization of a human orthotopic neuroblastoma xenograft
por: Stewart, Elizabeth, et al.
Publicado: (2015)

Surgery of non-spinal skeletal metastases in renal cell carcinoma
por: Ratasvuori, Maire, et al.
Publicado: (2016)

Characteristic Reconstitution of the Spinal Langerhans Cell Histiocytosis in Young Children
por: Nakamura, Naoyuki, et al.
Publicado: (2019)

Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma
por: Tomolonis, Julie A, et al.
Publicado: (2023)

The genetic tumor background is an important determinant for heterogeneous MYCN‐amplified neuroblastoma
por: Bogen, Dominik, et al.
Publicado: (2016)

SUN-930 A Case of Acromegaly Secondary to Ectopic Growth Hormone-Releasing Hormone (GHRH) Secretion from a Bronchial Neuroendocrine Tumour
por: Bahrami, Jasmine, et al.
Publicado: (2020)

Soft tissue extension increases the risk of local recurrence after curettage with adjuvants for giant-cell tumor of the long bones: A retrospective study of 93 patients
por: van der Heijden, L, et al.
Publicado: (2012)

Ectopic Cushing’s syndrome secondary to olfactory neuroblastoma
por: Yu, Kenny, et al.
Publicado: (2018)

Druggable epigenetic suppression of interferon-induced chemokine expression linked to MYCN amplification in neuroblastoma
por: Seier, Johanna A, et al.
Publicado: (2021)

The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer‐aided detection
por: Vicente‐Munuera, Pablo, et al.
Publicado: (2019)

The genomics and epigenetics of olfactory neuroblastoma: A systematic review
por: Kaur, Raman Preet, et al.
Publicado: (2021)

Small extracellular vesicles induce resistance to anti-GD2 immunotherapy unveiling tipifarnib as an adjunct to neuroblastoma immunotherapy
por: Liu, Xiaoming, et al.
Publicado: (2022)

G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment
por: Martinez Sanz, Paula, et al.
Publicado: (2021)

PSUN372 Insulinoma in an Elderly Woman with History of Distal Pancreatectomy: Treatment Challenges
por: Friedman, Sally B, et al.
Publicado: (2022)

Custom osteotomy guides for resection of a pelvic chondrosarcoma
por: Blakeney, William G, et al.
Publicado: (2014)

Metastatic adenocarcinoma of Proximal Femur treated by Custom made Hip Prosthesis
por: Pal, Chandra Prakash, et al.
Publicado: (2012)

Osteochondroma Arising from the Thoracic Transverse Process
por: Wenyuan, Ding, et al.
Publicado: (2009)

Computer-assisted surgery in orthopedic oncology: Technique, indications, and a descriptive study of 130 cases
por: Gerbers, Jasper G, et al.
Publicado: (2014)

Alarm symptoms of soft-tissue and bone sarcoma in patients referred to a specialist center
por: Dyrop, Heidi B, et al.
Publicado: (2014)

Pelvic irradiation does not increase the risk of hip replacement in patients with gynecological cancer: A cohort study based on 8,507 patients
por: Dybvik, Eva, et al.
Publicado: (2014)

Comparison of allograft-prosthetic composite reconstruction and modular prosthetic replacement in proximal femur bone tumors: Functional assessment by gait analysis in 20 patients
por: Benedetti, Maria Grazia, et al.
Publicado: (2013)

Improved prognosis in soft-tissue sarcoma of extremity and trunk wall: Comparison of patients diagnosed during 1998–2001 and 2005–2010 in Finland
por: Sampo, Mika M, et al.
Publicado: (2017)

Imaging investigations before referral to a sarcoma center delay the final diagnosis of musculoskeletal sarcoma
por: Dyrop, Heidi Buvarp, et al.
Publicado: (2017)

The Scandinavian Sarcoma Group Central Register: 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma
por: Trovik, Clement, et al.
Publicado: (2017)

Commentary: Laser Interstitial Thermal Therapy for First-Line Treatment of Surgically Accessible Recurrent Glioblastoma: Outcomes Compared With a Surgical Cohort
por: Schwalb, Allison M., et al.
Publicado: (2022)

Do’s and Don’ts in Primary Aneurysmal Bone Cysts of the Proximal Femur in Children and Adolescents: Retrospective Multicenter EPOS Study of 79 Patients
por: van Geloven, Thomas P.G., et al.
Publicado: (2023)

Effective Cytotoxicity of Dendritic Cells against Established T Cell Lymphomas in Mice
por: Dubois, Sigrid, et al.
Publicado: (2021)

SAT-340 27-Hydroxycholesterol Acts on Myeloid Cells to Inhibit T Cell Expansion
por: Ma, Liqian, et al.
Publicado: (2019)

SUN-907 Dual Ectopic Gastrin and ACTH Secretion Leading to Combined Zollinger-Ellison Syndrome and Cushing’s Syndrome in a Patient with Metastatic Neuroendocrine Pancreatic Tumor
por: Kwak, Leigh, et al.
Publicado: (2020)

IFN-γ treatment protocol for MHC-I(lo)/PD-L1(+) pancreatic tumor cells selectively restores their TAP-mediated presentation competence and CD8 T-cell priming potential
por: Stifter, Katja, et al.
Publicado: (2020)

L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells
por: Douglass, Matthew S., et al.
Publicado: (2021)

SUN-328 Non-Islet Cell Tumor-Induced Hypoglycemia in a Patient with IGF-2 Producing Spindle Cell Neoplasm
por: Nagy, Rea, et al.
Publicado: (2019)

THU542 Inhibiting Oxidosqualene Cyclase Suppresses Cancer Stem-like Cells And Growth Of Epithelial Ovarian Cancer Cells In Vitro And In Vivo
por: Liang, Yayun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nnsipqkv5ieuefguj3uan90pc6