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Case Report: Detection of Double ROS1 Translocations, SDC4-ROS1 and ROS1-GK, in a Lung Adenocarcinoma Patient and Response to Crizotinib

ROS1 rearrangement, identified in ~2% of non-small cell lung cancer (NSCLC), has defined a distinctive molecular subtype. Patients with ROS1 fusion have been shown to be highly sensitive to treatment with crizotinib. However, the efficacy of crizotinib in NSCLC patients with double ROS1 fusions rema...

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Detalles Bibliográficos
Autores principales:	Xu, Long, Chen, Xiaoxia, Huo, Hong, Liu, Yongye, Yang, Xiaodan, Gu, Dejian, Yuan, Mingming, Zhang, Min, Chen, Rongrong, Wang, Jiayin, Zheng, Zhendong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488083/ https://www.ncbi.nlm.nih.gov/pubmed/34616749 http://dx.doi.org/10.3389/fmed.2021.649177

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