Intelligence Quotient Variability in Klinefelter Syndrome Is Associated With GTPBP6 Expression Under Regulation of X-Chromosome Inactivation Pattern

Klinefelter syndrome (KS) displays a broad dysmorphological, endocrinological, and neuropsychological clinical spectrum. We hypothesized that the neurocognitive dysfunction present in KS relies on an imbalance in X-chromosome gene expression. Thus, the X-chromosome inactivation (XCI) pattern and neu...

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Detalles Bibliográficos
Autores principales: Simonetti, Luciane, Ferreira, Lucas G. A., Vidi, Angela Cristina, de Souza, Janaina Sena, Kunii, Ilda S., Melaragno, Maria Isabel, de Mello, Claudia Berlim, Carvalheira, Gianna, Dias da Silva, Magnus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488338/
https://www.ncbi.nlm.nih.gov/pubmed/34616429
http://dx.doi.org/10.3389/fgene.2021.724625

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