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SARS-CoV-2 Coronavirus Spike Protein-Induced Apoptosis, Inflammatory, and Oxidative Stress Responses in THP-1-Like-Macrophages: Potential Role of Angiotensin-Converting Enzyme Inhibitor (Perindopril)

A purified spike (S) glycoprotein of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) coronavirus was used to study its effects on THP-1 macrophages, peripheral blood mononuclear cells (PBMCs), and HUVEC cells. The S protein mediates the entry of SARS-CoV-2 into cells through bin...

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Detalles Bibliográficos
Autores principales:	Barhoumi, Tlili, Alghanem, Bandar, Shaibah, Hayat, Mansour, Fatmah A., Alamri, Hassan S., Akiel, Maaged A., Alroqi, Fayhan, Boudjelal, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488399/ https://www.ncbi.nlm.nih.gov/pubmed/34616396 http://dx.doi.org/10.3389/fimmu.2021.728896

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