A Case Report of Familial Extramammary Paget's Disease in Female Siblings

Extramammary Paget's disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area. Familial form of EMPD is extremely rare. Several g...

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Detalles Bibliográficos
Autores principales: Rutnumnoi, Thanachat, Leeyaphan, Charussri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488423/
https://www.ncbi.nlm.nih.gov/pubmed/34703424
http://dx.doi.org/10.1159/000514253
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author Rutnumnoi, Thanachat
Leeyaphan, Charussri
author_facet Rutnumnoi, Thanachat
Leeyaphan, Charussri
author_sort Rutnumnoi, Thanachat
collection PubMed
description Extramammary Paget's disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area. Familial form of EMPD is extremely rare. Several genetic mutations have been proposed but specific modes of inheritance are still unknown. This article reports two cases of familial extramammary Paget's disease in female siblings.
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spelling pubmed-84884232021-10-25 A Case Report of Familial Extramammary Paget's Disease in Female Siblings Rutnumnoi, Thanachat Leeyaphan, Charussri Case Rep Dermatol Case Series Extramammary Paget's disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area. Familial form of EMPD is extremely rare. Several genetic mutations have been proposed but specific modes of inheritance are still unknown. This article reports two cases of familial extramammary Paget's disease in female siblings. S. Karger AG 2021-03-22 /pmc/articles/PMC8488423/ /pubmed/34703424 http://dx.doi.org/10.1159/000514253 Text en Copyright © 2021 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Series
Rutnumnoi, Thanachat
Leeyaphan, Charussri
A Case Report of Familial Extramammary Paget's Disease in Female Siblings
title A Case Report of Familial Extramammary Paget's Disease in Female Siblings
title_full A Case Report of Familial Extramammary Paget's Disease in Female Siblings
title_fullStr A Case Report of Familial Extramammary Paget's Disease in Female Siblings
title_full_unstemmed A Case Report of Familial Extramammary Paget's Disease in Female Siblings
title_short A Case Report of Familial Extramammary Paget's Disease in Female Siblings
title_sort case report of familial extramammary paget's disease in female siblings
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488423/
https://www.ncbi.nlm.nih.gov/pubmed/34703424
http://dx.doi.org/10.1159/000514253
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