Circulating miRNome profiling data in Behçet's syndrome

We conducted a screening analysis to assess the presence of a characteristic extracellular circulating microRNAs (ci-miRNAs) profile in Behçet's syndrome (BS). Total RNA was extracted from platelets-free plasma (PFP) samples obtained from 16 BS patients and 18 healthy controls. Ci-miRNAs profil...

Descripción completa

Detalles Bibliográficos
Autores principales: Bagni, Giacomo, Emmi, Giacomo, Lastraioli, Elena, Di Patti, Francesca, Silvestri, Elena, Guerriero, Angela, Pillozzi, Serena, Niccolai, Elena, Amedei, Amedeo, Emmi, Lorenzo, Prisco, Domenico, Arcangeli, Annarosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488478/
https://www.ncbi.nlm.nih.gov/pubmed/34632024
http://dx.doi.org/10.1016/j.dib.2021.107435
Descripción
Sumario:We conducted a screening analysis to assess the presence of a characteristic extracellular circulating microRNAs (ci-miRNAs) profile in Behçet's syndrome (BS). Total RNA was extracted from platelets-free plasma (PFP) samples obtained from 16 BS patients and 18 healthy controls. Ci-miRNAs profiling was conducted by using dedicated Agilent microarray hybridization and data extraction technology. Statistical analysis of data extracted from microarray scanning revealed the deregulation of 36 ci-miRNAs, which turned out be differentially expressed between BS patients and healthy controls. Detailed experimental methods and data analysis were described here. The raw and normalized microarray data were deposited into Gene Expression Omnibus (GEO) under accession number GSE145191.

Ejemplares similares