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Amyloid-β peptide dimers undergo a random coil to β-sheet transition in the aqueous phase but not at the neuronal membrane
Mounting evidence suggests that the neuronal cell membrane is the main site of oligomer-mediated neuronal toxicity of amyloid- [Formula: see text] peptides in Alzheimer’s disease. To gain a detailed understanding of the mutual interference of amyloid- [Formula: see text] oligomers and the neuronal m...
Autores principales: | Fatafta, Hebah, Khaled, Mohammed, Owen, Michael C., Sayyed-Ahmad, Abdallah, Strodel, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488611/ https://www.ncbi.nlm.nih.gov/pubmed/34544868 http://dx.doi.org/10.1073/pnas.2106210118 |
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