Shotgun scanning glycomutagenesis: A simple and efficient strategy for constructing and characterizing neoglycoproteins

As a common protein modification, asparagine-linked (N-linked) glycosylation has the capacity to greatly influence the biological and biophysical properties of proteins. However, the routine use of glycosylation as a strategy for engineering proteins with advantageous properties is limited by our in...

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Detalles Bibliográficos
Autores principales: Li, Mingji, Zheng, Xiaolu, Shanker, Sudhanshu, Jaroentomeechai, Thapakorn, Moeller, Tyler D., Hulbert, Sophia W., Koçer, Ilkay, Byrne, Josef, Cox, Emily C., Fu, Qin, Zhang, Sheng, Labonte, Jason W., Gray, Jeffrey J., DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488656/
https://www.ncbi.nlm.nih.gov/pubmed/34551980
http://dx.doi.org/10.1073/pnas.2107440118

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