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Molecular characterization of a complex of apoptosis-inducing factor 1 with cytochrome c oxidase of the mitochondrial respiratory chain

Combining mass spectrometry–based chemical cross-linking and complexome profiling, we analyzed the interactome of heart mitochondria. We focused on complexes of oxidative phosphorylation and found that dimeric apoptosis-inducing factor 1 (AIFM1) forms a defined complex with ∼10% of monomeric cytochr...

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Detalles Bibliográficos
Autores principales: Hevler, Johannes F., Zenezeni Chiozzi, Riccardo, Cabrera-Orefice, Alfredo, Brandt, Ulrich, Arnold, Susanne, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488679/
https://www.ncbi.nlm.nih.gov/pubmed/34548399
http://dx.doi.org/10.1073/pnas.2106950118