Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors

BACKGROUND: Atypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive CNS tumors of infancy and early childhood. Hallmark is the surprisingly simple genome with inactivating mutations or deletions in the SMARCB1 gene as the oncogenic driver. Nevertheless, AT/RTs are infiltrated by immune cells...

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Detalles Bibliográficos
Autores principales: Marcu, Ana, Schlosser, Andreas, Keupp, Anne, Trautwein, Nico, Johann, Pascal, Wölfl, Matthias, Lager, Johanna, Monoranu, Camelia Maria, Walz, Juliane S, Henkel, Lisa M, Krauß, Jürgen, Ebinger, Martin, Schuhmann, Martin, Thomale, Ulrich Wilhelm, Pietsch, Torsten, Klinker, Erdwine, Schlegel, Paul G, Oyen, Florian, Reisner, Yair, Rammensee, Hans-Georg, Eyrich, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488729/
https://www.ncbi.nlm.nih.gov/pubmed/34599019
http://dx.doi.org/10.1136/jitc-2021-003404

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