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MRI findings seen in serous atrophy of bone marrow

An 85-year-old man was referred for an MRI scan of the pelvis for further evaluation of a suspected left neck of femur fracture, which was regarded as equivocal on plain radiograph and CT. The initial MRI demonstrated unusual appearances of the visualised bone marrow and subcutaneous adipose tissue...

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Autores principales: Kalamar, Vilim, Davies, Alun, Wright, Peter, Suresh, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488742/
https://www.ncbi.nlm.nih.gov/pubmed/34598960
http://dx.doi.org/10.1136/bcr-2021-243770
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author Kalamar, Vilim
Davies, Alun
Wright, Peter
Suresh, Priya
author_facet Kalamar, Vilim
Davies, Alun
Wright, Peter
Suresh, Priya
author_sort Kalamar, Vilim
collection PubMed
description An 85-year-old man was referred for an MRI scan of the pelvis for further evaluation of a suspected left neck of femur fracture, which was regarded as equivocal on plain radiograph and CT. The initial MRI demonstrated unusual appearances of the visualised bone marrow and subcutaneous adipose tissue and was initially misinterpreted as a technical malfunction of the scanner. However, a repeat study on a different scanner the following day once again demonstrated the same appearances. The appearances were consistent with serous atrophy of bone marrow, a non-neoplastic disorder of the bone marrow, which is most commonly seen in severe anorexia nervosa or cachexia. These unusual, but distinct, bone marrow and subcutaneous adipose tissue appearances, which are specific to MRI, have been colloquially termed as the ‘flip-flop’ effect.
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spelling pubmed-84887422021-10-14 MRI findings seen in serous atrophy of bone marrow Kalamar, Vilim Davies, Alun Wright, Peter Suresh, Priya BMJ Case Rep Case Report An 85-year-old man was referred for an MRI scan of the pelvis for further evaluation of a suspected left neck of femur fracture, which was regarded as equivocal on plain radiograph and CT. The initial MRI demonstrated unusual appearances of the visualised bone marrow and subcutaneous adipose tissue and was initially misinterpreted as a technical malfunction of the scanner. However, a repeat study on a different scanner the following day once again demonstrated the same appearances. The appearances were consistent with serous atrophy of bone marrow, a non-neoplastic disorder of the bone marrow, which is most commonly seen in severe anorexia nervosa or cachexia. These unusual, but distinct, bone marrow and subcutaneous adipose tissue appearances, which are specific to MRI, have been colloquially termed as the ‘flip-flop’ effect. BMJ Publishing Group 2021-10-01 /pmc/articles/PMC8488742/ /pubmed/34598960 http://dx.doi.org/10.1136/bcr-2021-243770 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Report
Kalamar, Vilim
Davies, Alun
Wright, Peter
Suresh, Priya
MRI findings seen in serous atrophy of bone marrow
title MRI findings seen in serous atrophy of bone marrow
title_full MRI findings seen in serous atrophy of bone marrow
title_fullStr MRI findings seen in serous atrophy of bone marrow
title_full_unstemmed MRI findings seen in serous atrophy of bone marrow
title_short MRI findings seen in serous atrophy of bone marrow
title_sort mri findings seen in serous atrophy of bone marrow
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488742/
https://www.ncbi.nlm.nih.gov/pubmed/34598960
http://dx.doi.org/10.1136/bcr-2021-243770
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