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MRI findings seen in serous atrophy of bone marrow
An 85-year-old man was referred for an MRI scan of the pelvis for further evaluation of a suspected left neck of femur fracture, which was regarded as equivocal on plain radiograph and CT. The initial MRI demonstrated unusual appearances of the visualised bone marrow and subcutaneous adipose tissue...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488742/ https://www.ncbi.nlm.nih.gov/pubmed/34598960 http://dx.doi.org/10.1136/bcr-2021-243770 |
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author | Kalamar, Vilim Davies, Alun Wright, Peter Suresh, Priya |
author_facet | Kalamar, Vilim Davies, Alun Wright, Peter Suresh, Priya |
author_sort | Kalamar, Vilim |
collection | PubMed |
description | An 85-year-old man was referred for an MRI scan of the pelvis for further evaluation of a suspected left neck of femur fracture, which was regarded as equivocal on plain radiograph and CT. The initial MRI demonstrated unusual appearances of the visualised bone marrow and subcutaneous adipose tissue and was initially misinterpreted as a technical malfunction of the scanner. However, a repeat study on a different scanner the following day once again demonstrated the same appearances. The appearances were consistent with serous atrophy of bone marrow, a non-neoplastic disorder of the bone marrow, which is most commonly seen in severe anorexia nervosa or cachexia. These unusual, but distinct, bone marrow and subcutaneous adipose tissue appearances, which are specific to MRI, have been colloquially termed as the ‘flip-flop’ effect. |
format | Online Article Text |
id | pubmed-8488742 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-84887422021-10-14 MRI findings seen in serous atrophy of bone marrow Kalamar, Vilim Davies, Alun Wright, Peter Suresh, Priya BMJ Case Rep Case Report An 85-year-old man was referred for an MRI scan of the pelvis for further evaluation of a suspected left neck of femur fracture, which was regarded as equivocal on plain radiograph and CT. The initial MRI demonstrated unusual appearances of the visualised bone marrow and subcutaneous adipose tissue and was initially misinterpreted as a technical malfunction of the scanner. However, a repeat study on a different scanner the following day once again demonstrated the same appearances. The appearances were consistent with serous atrophy of bone marrow, a non-neoplastic disorder of the bone marrow, which is most commonly seen in severe anorexia nervosa or cachexia. These unusual, but distinct, bone marrow and subcutaneous adipose tissue appearances, which are specific to MRI, have been colloquially termed as the ‘flip-flop’ effect. BMJ Publishing Group 2021-10-01 /pmc/articles/PMC8488742/ /pubmed/34598960 http://dx.doi.org/10.1136/bcr-2021-243770 Text en © BMJ Publishing Group Limited 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Case Report Kalamar, Vilim Davies, Alun Wright, Peter Suresh, Priya MRI findings seen in serous atrophy of bone marrow |
title | MRI findings seen in serous atrophy of bone marrow |
title_full | MRI findings seen in serous atrophy of bone marrow |
title_fullStr | MRI findings seen in serous atrophy of bone marrow |
title_full_unstemmed | MRI findings seen in serous atrophy of bone marrow |
title_short | MRI findings seen in serous atrophy of bone marrow |
title_sort | mri findings seen in serous atrophy of bone marrow |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488742/ https://www.ncbi.nlm.nih.gov/pubmed/34598960 http://dx.doi.org/10.1136/bcr-2021-243770 |
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