A protocol to quantify chromatin compaction with confocal and super-resolution microscopy in cultured cells
Here, we describe three complementary microscopy-based approaches to quantify morphological changes of chromatin organization in cultured adherent cells: the analysis of the coefficient of variation of DNA, the measurement of DNA-free nuclear areas, and the quantification of chromatin-associated pro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488755/ https://www.ncbi.nlm.nih.gov/pubmed/34632419 http://dx.doi.org/10.1016/j.xpro.2021.100865 |