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A Phase I Trial of Oxaliplatin, Irinotecan, and S‐1 Combination Therapy (OX‐IRIS) as Chemotherapy for Unresectable Pancreatic Cancer (HGCSG 1403)
LESSONS LEARNED: Because S‐1 is orally administered, OX‐IRIS does not necessitate the continuous infusion of 5‐FU and is more convenient. The recommended dose of OX‐IRIS was determined to be level −1 (oxaliplatin, 65 mg/m(2); irinotecan, 100 mg/m(2); S‐1, 80 mg/m(2)), which has manageable safety and...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8488776/ https://www.ncbi.nlm.nih.gov/pubmed/34050586 http://dx.doi.org/10.1002/onco.13838 |