DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

BACKGROUND: Current clinical guidelines suggest that breast cancers with low hormone receptor expression (LowHR) in 1–10% of tumor cells should be regarded as hormone receptor positive. However, clinical data show that these patients have worse outcome compared to patients with hormone receptor expr...

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Detalles Bibliográficos
Autores principales: Jurmeister, Philipp, Weber, Karsten, Villegas, Sonia, Karn, Thomas, Untch, Michael, Thieme, Anne, Müller, Volkmar, Taube, Eliane, Fasching, Peter, Schmitt, Wolfgang D., Marmé, Frederik, Stickeler, Elmar, Sinn, Bruno V., Jank, Paul, Schem, Christian, Klauschen, Frederick, van Mackelenbergh, Marion, Denkert, Carsten, Loibl, Sibylle, Capper, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489064/
https://www.ncbi.nlm.nih.gov/pubmed/34602069
http://dx.doi.org/10.1186/s13148-021-01176-5

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