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Adiponectin ameliorates lung ischemia–reperfusion injury through SIRT1-PINK1 signaling-mediated mitophagy in type 2 diabetic rats

BACKGROUND: Diabetes mellitus (DM) is a key contributing factor to poor survival in lung transplantation recipients. Mitochondrial dysfunction is recognized as a critical mediator in the pathogenesis of diabetic lung ischemia–reperfusion (IR) injury. The protective effects of adiponectin have been d...

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Detalles Bibliográficos
Autores principales:	Jiang, Tao, Liu, Tianhua, Deng, Xijin, Ding, Wengang, Yue, Ziyong, Yang, Wanchao, Lv, Xiangqi, Li, Wenzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489101/ https://www.ncbi.nlm.nih.gov/pubmed/34602075 http://dx.doi.org/10.1186/s12931-021-01855-0

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