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Systemic and intrathecal baclofen produce bladder antinociception in rats

BACKGROUND: Baclofen, a clinically available GABA(B) receptor agonist, produces non-opioid analgesia in multiple models of pain but has not been tested for effects on bladder nociception. METHODS: A series of experiments examined the effects of systemic and spinally administered baclofen on bladder...

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Detalles Bibliográficos
Autores principales: Ness, Timothy J., Randich, Alan, Su, Xin, DeWitte, Cary, Hildebrand, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489106/
https://www.ncbi.nlm.nih.gov/pubmed/34607587
http://dx.doi.org/10.1186/s12894-021-00899-0

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