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The anti-osteosarcoma effect from panax notoginseng saponins by inhibiting the G(0) / G(1) phase in the cell cycle and affecting p53-mediated autophagy and mitochondrial apoptosis

Osteosarcoma is the most common primary bone malignancy, and current chemotherapy sessions against it often induce severe complications in patients. Thus, it is necessary to develop new and effective antineoplastic agents with fewer side effects. Panax notoginseng saponins (PNS) are the active compo...

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Detalles Bibliográficos
Autores principales: Han, Guangtao, Zhang, Yubiao, Liu, Ting, Li, Jianping, Li, Haohuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489146/
https://www.ncbi.nlm.nih.gov/pubmed/34659528
http://dx.doi.org/10.7150/jca.54602

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