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The anti-osteosarcoma effect from panax notoginseng saponins by inhibiting the G(0) / G(1) phase in the cell cycle and affecting p53-mediated autophagy and mitochondrial apoptosis
Osteosarcoma is the most common primary bone malignancy, and current chemotherapy sessions against it often induce severe complications in patients. Thus, it is necessary to develop new and effective antineoplastic agents with fewer side effects. Panax notoginseng saponins (PNS) are the active compo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489146/ https://www.ncbi.nlm.nih.gov/pubmed/34659528 http://dx.doi.org/10.7150/jca.54602 |