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L-cell Arntl is required for rhythmic glucagon-like peptide-1 secretion and maintenance of intestinal homeostasis

OBJECTIVE: Recent studies using whole-body clock-disrupted animals identified a disruption in the circadian rhythm of the intestinal L-cell incretin hormone, glucagon-like peptide-1 (GLP-1). Although GLP-1 plays an essential role in metabolism through enhancement of both glucose-stimulated insulin s...

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Detalles Bibliográficos
Autores principales: Martchenko, Sarah E., Martchenko, Alexandre, Biancolin, Andrew D., Waller, Alison, Brubaker, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489154/
https://www.ncbi.nlm.nih.gov/pubmed/34520858
http://dx.doi.org/10.1016/j.molmet.2021.101340

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