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Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry
OBJECTIVE: The objective of this study was to better understand the pathophysiology and underlying genetic mechanisms behind two abdominal aortic aneurysm (AAA) subtypes using computed tomographic imaging in combination with whole genome sequencing. METHODS: Patients with a known AAA and European an...
Autores principales: | Miner, Grace H., Renton, Alan E., Taubenfeld, Ella, Tadros, Rami O., Marcora, Edoardo, Lookstein, Robert A., Faries, Peter L., Marin, Michael L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489199/ https://www.ncbi.nlm.nih.gov/pubmed/34617051 http://dx.doi.org/10.1016/j.jvssci.2020.09.001 |
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