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Inhibition of angiotensin-induced aortic aneurysm by metformin in apolipoprotein E–deficient mice

OBJECTIVE: Metformin is associated with a reduced incidence and growth of abdominal aortic aneurysms (AAAs). The aim of the present study was to investigate the inhibitory effects of metformin on AAA development and possible underlying mechanisms in experimentally induced AAAs in mice, along with th...

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Detalles Bibliográficos
Autores principales: Kunath, Anne, Unosson, Jon, Friederich-Persson, Malou, Bjarnegård, Niclas, Becirovic-Agic, Mediha, Björck, Martin, Mani, Kevin, Wanhainen, Anders, Wågsäter, Dick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489247/
https://www.ncbi.nlm.nih.gov/pubmed/34617056
http://dx.doi.org/10.1016/j.jvssci.2020.11.031