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Inhibition of angiotensin-induced aortic aneurysm by metformin in apolipoprotein E–deficient mice
OBJECTIVE: Metformin is associated with a reduced incidence and growth of abdominal aortic aneurysms (AAAs). The aim of the present study was to investigate the inhibitory effects of metformin on AAA development and possible underlying mechanisms in experimentally induced AAAs in mice, along with th...
Autores principales: | Kunath, Anne, Unosson, Jon, Friederich-Persson, Malou, Bjarnegård, Niclas, Becirovic-Agic, Mediha, Björck, Martin, Mani, Kevin, Wanhainen, Anders, Wågsäter, Dick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489247/ https://www.ncbi.nlm.nih.gov/pubmed/34617056 http://dx.doi.org/10.1016/j.jvssci.2020.11.031 |
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