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Delivering embryos following 10 years of cryopreservation, using unpaired freeze/thaw techniques: A case report

Although frozen embryo transfer is a widely established route for assisted reproduction, successful frozen embryo transfer using embryos that have undergone long term cryopreservation remains relatively unexplored, and its efficacy remains a matter of some debate. This case report describes two succ...

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Detalles Bibliográficos
Autores principales: Melantonio, Priscila, Attivo, Jessica, Gomes, Alecsandra P., Bonetti, Tatiana C.S., Monteleone, Pedro A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489820/
https://www.ncbi.nlm.nih.gov/pubmed/34106560
http://dx.doi.org/10.5935/1518-0557.20210015
Descripción
Sumario:Although frozen embryo transfer is a widely established route for assisted reproduction, successful frozen embryo transfer using embryos that have undergone long term cryopreservation remains relatively unexplored, and its efficacy remains a matter of some debate. This case report describes two successful frozen embryo transfer conceptions in the same patient, one after 3 months of cryopreservation and the second 10 years after cryopreservation. These embryos were cryopreserved using the slow freezing technique and were thawed using an unpaired technique (ultra-rapid warming) after 10 years of storage.