Cargando…

Nuclear SR-protein mediated mRNA quality control is continued in cytoplasmic nonsense-mediated decay

One important task of eukaryotic cells is to translate only mRNAs that were correctly processed to prevent the production of truncated proteins, found in neurodegenerative diseases and cancer. Nuclear quality control of splicing requires the SR-like proteins Gbp2 and Hrb1 in S. cerevisiae, where the...

Descripción completa

Detalles Bibliográficos
Autores principales: Grosse, Sebastian, Lu, Yen-Yun, Coban, Ivo, Neumann, Bettina, Krebber, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489946/
https://www.ncbi.nlm.nih.gov/pubmed/33406982
http://dx.doi.org/10.1080/15476286.2020.1851506