Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants

The study tested the hypothesis that harboring high levels of histo-blood group antigen-expressing Enerobactero cloacae is a risk factor for norovirus diarrhea. The fecal E. cloacae abundance in diarrheic norovirus positive (DNP), non-diarrheic norovirus negative (NDNN), diarrhea norovirus negative...

Descripción completa

Detalles Bibliográficos
Autores principales: Magwira, Cliff A, Steele, Duncan, Seheri, ML
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489948/
https://www.ncbi.nlm.nih.gov/pubmed/34586017
http://dx.doi.org/10.1080/19490976.2021.1979876
_version_ 1784578426639745024
author Magwira, Cliff A
Steele, Duncan
Seheri, ML
author_facet Magwira, Cliff A
Steele, Duncan
Seheri, ML
author_sort Magwira, Cliff A
collection PubMed
description The study tested the hypothesis that harboring high levels of histo-blood group antigen-expressing Enerobactero cloacae is a risk factor for norovirus diarrhea. The fecal E. cloacae abundance in diarrheic norovirus positive (DNP), non-diarrheic norovirus negative (NDNN), diarrhea norovirus negative (DNN), and non-diarrhea norovirus positive (NDNP) infants was determined by qPCR, and the risk of norovirus diarrhea was assessed by logistical regression. DNP infants contained significantly higher counts of E. cloacae than NDNN and DNN infants, p = .0294, and 0.0001, respectively. The risk of norovirus diarrhea was significantly high in infants with higher counts of E. cloacae than those with lower counts, p = .009. Harboring higher counts of E. cloacae is a risk factor for norovirus diarrhea.
format Online
Article
Text
id pubmed-8489948
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-84899482021-10-05 Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants Magwira, Cliff A Steele, Duncan Seheri, ML Gut Microbes Letter to the Editor The study tested the hypothesis that harboring high levels of histo-blood group antigen-expressing Enerobactero cloacae is a risk factor for norovirus diarrhea. The fecal E. cloacae abundance in diarrheic norovirus positive (DNP), non-diarrheic norovirus negative (NDNN), diarrhea norovirus negative (DNN), and non-diarrhea norovirus positive (NDNP) infants was determined by qPCR, and the risk of norovirus diarrhea was assessed by logistical regression. DNP infants contained significantly higher counts of E. cloacae than NDNN and DNN infants, p = .0294, and 0.0001, respectively. The risk of norovirus diarrhea was significantly high in infants with higher counts of E. cloacae than those with lower counts, p = .009. Harboring higher counts of E. cloacae is a risk factor for norovirus diarrhea. Taylor & Francis 2021-09-29 /pmc/articles/PMC8489948/ /pubmed/34586017 http://dx.doi.org/10.1080/19490976.2021.1979876 Text en © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Magwira, Cliff A
Steele, Duncan
Seheri, ML
Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants
title Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants
title_full Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants
title_fullStr Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants
title_full_unstemmed Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants
title_short Norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing Enterobacter cloacae among black South African infants
title_sort norovirus diarrhea is significantly associated with higher counts of fecal histo-blood group antigen expressing enterobacter cloacae among black south african infants
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489948/
https://www.ncbi.nlm.nih.gov/pubmed/34586017
http://dx.doi.org/10.1080/19490976.2021.1979876
work_keys_str_mv AT magwiracliffa norovirusdiarrheaissignificantlyassociatedwithhighercountsoffecalhistobloodgroupantigenexpressingenterobactercloacaeamongblacksouthafricaninfants
AT steeleduncan norovirusdiarrheaissignificantlyassociatedwithhighercountsoffecalhistobloodgroupantigenexpressingenterobactercloacaeamongblacksouthafricaninfants
AT seheriml norovirusdiarrheaissignificantlyassociatedwithhighercountsoffecalhistobloodgroupantigenexpressingenterobactercloacaeamongblacksouthafricaninfants

Ejemplares similares