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From APC to the genetics of hereditary and familial colon cancer syndromes

Hereditary colorectal cancer (CRC) syndromes attributable to high penetrance mutations represent 9–26% of young-onset CRC cases. The clinical significance of many of these mutations is understood well enough to be used in diagnostics and as an aid in patient care. However, despite the advances made...

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Detalles Bibliográficos
Autores principales: Olkinuora, Alisa P, Peltomäki, Päivi T, Aaltonen, Lauri A, Rajamäki, Kristiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490010/
https://www.ncbi.nlm.nih.gov/pubmed/34329396
http://dx.doi.org/10.1093/hmg/ddab208