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Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm

Aiming at the difficulty in setting the support threshold for sequential pattern mining algorithms and improving the effectiveness of the support threshold setting without the guidance of domain experts' experience, an improved SPADE (sequential pattern discovery using equivalence classes) algo...

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Autor principal: Li, Jiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490047/
https://www.ncbi.nlm.nih.gov/pubmed/34616526
http://dx.doi.org/10.1155/2021/1072446
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author Li, Jiawei
author_facet Li, Jiawei
author_sort Li, Jiawei
collection PubMed
description Aiming at the difficulty in setting the support threshold for sequential pattern mining algorithms and improving the effectiveness of the support threshold setting without the guidance of domain experts' experience, an improved SPADE (sequential pattern discovery using equivalence classes) algorithm is proposed. By analyzing the relationship between the number of frequent sequences and the support threshold, the support threshold is dynamically selected. Using the electronic medical record data from a medical centre, the time-series relationship of the drugs taken by hypertension patients was extracted as the drug sequence dataset. By determining the optimal support threshold of the dataset, the frequent sequence set is mined, and the sequence rules are generated from the obtained regular sequences to visualize the sequence rules. The sequence rules of medication for hypertensive patients were combined with the patients' physical indicators for the recommendation. For patients with obstetric hypertension, a combination of nifedipine and captopril is recommended. Through the comparison of the observation group and control group, we study the curative effect of various drugs. The results showed that the total effective rate of the observation group was about 96.6%; compared with the control group, the result indicated that the difference was significant (P < 0.05). The comparison of blood pressure levels between the two groups after treatment also showed that the results of the observation group were ideal (P < 0.05). In addition, the incidence of postpartum haemorrhage and perinatal complications in the observation group was also significantly reduced (P < 0.05). Therefore, the combination of medication for pregnancy hypertension syndrome can effectively improve the treatment effect of the disease and reduce the rate of postpartum haemorrhage and the incidence of perinatal complications.
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spelling pubmed-84900472021-10-05 Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm Li, Jiawei J Healthc Eng Research Article Aiming at the difficulty in setting the support threshold for sequential pattern mining algorithms and improving the effectiveness of the support threshold setting without the guidance of domain experts' experience, an improved SPADE (sequential pattern discovery using equivalence classes) algorithm is proposed. By analyzing the relationship between the number of frequent sequences and the support threshold, the support threshold is dynamically selected. Using the electronic medical record data from a medical centre, the time-series relationship of the drugs taken by hypertension patients was extracted as the drug sequence dataset. By determining the optimal support threshold of the dataset, the frequent sequence set is mined, and the sequence rules are generated from the obtained regular sequences to visualize the sequence rules. The sequence rules of medication for hypertensive patients were combined with the patients' physical indicators for the recommendation. For patients with obstetric hypertension, a combination of nifedipine and captopril is recommended. Through the comparison of the observation group and control group, we study the curative effect of various drugs. The results showed that the total effective rate of the observation group was about 96.6%; compared with the control group, the result indicated that the difference was significant (P < 0.05). The comparison of blood pressure levels between the two groups after treatment also showed that the results of the observation group were ideal (P < 0.05). In addition, the incidence of postpartum haemorrhage and perinatal complications in the observation group was also significantly reduced (P < 0.05). Therefore, the combination of medication for pregnancy hypertension syndrome can effectively improve the treatment effect of the disease and reduce the rate of postpartum haemorrhage and the incidence of perinatal complications. Hindawi 2021-09-27 /pmc/articles/PMC8490047/ /pubmed/34616526 http://dx.doi.org/10.1155/2021/1072446 Text en Copyright © 2021 Jiawei Li. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Jiawei
Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm
title Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm
title_full Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm
title_fullStr Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm
title_full_unstemmed Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm
title_short Study on the Clinical Characteristics and Treatment of Obstetric Hypertension with Sequence Pattern Mining Algorithm
title_sort study on the clinical characteristics and treatment of obstetric hypertension with sequence pattern mining algorithm
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490047/
https://www.ncbi.nlm.nih.gov/pubmed/34616526
http://dx.doi.org/10.1155/2021/1072446
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