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Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C

Myocarditis has a wide array of clinical presentations ranging from asymptomatic to sudden cardiac death. Pediatric myocarditis is a rare disease, with an estimated annual incidence of 1 to 2 per 100,000 children though its true prevalence remains unknown due to its variable and often subclinical pr...

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Detalles Bibliográficos
Autores principales: Shah, Hemali P., Frye, Richard, Chang, Sunny, Faherty, Erin, Steele, Jeremy, Karnik, Ruchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490073/
https://www.ncbi.nlm.nih.gov/pubmed/34616578
http://dx.doi.org/10.1155/2021/4797498
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author Shah, Hemali P.
Frye, Richard
Chang, Sunny
Faherty, Erin
Steele, Jeremy
Karnik, Ruchika
author_facet Shah, Hemali P.
Frye, Richard
Chang, Sunny
Faherty, Erin
Steele, Jeremy
Karnik, Ruchika
author_sort Shah, Hemali P.
collection PubMed
description Myocarditis has a wide array of clinical presentations ranging from asymptomatic to sudden cardiac death. Pediatric myocarditis is a rare disease, with an estimated annual incidence of 1 to 2 per 100,000 children though its true prevalence remains unknown due to its variable and often subclinical presentation. The diagnosis of myocarditis is challenging in the era of COVID-19 and Multisystem Inflammatory Syndrome in Children (MIS-C), which can have overlapping clinical conundrum. Here, we present a case of a 17-year-old male presenting with chest tightness, shortness of breath, and electrocardiogram (EKG) findings concerning for myocardial injury along with elevated inflammatory markers such as D-dimer, ESR (Erythrocyte Sedimentation Rate), and CRP (C-Reactive Protein). We discuss the key elements of our clinical experience with this case and review the literature for pediatric myocarditis, with a focus on differentiating it from MIS-C in the current COVID-19 pandemic era.
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spelling pubmed-84900732021-10-05 Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C Shah, Hemali P. Frye, Richard Chang, Sunny Faherty, Erin Steele, Jeremy Karnik, Ruchika Case Rep Pediatr Case Report Myocarditis has a wide array of clinical presentations ranging from asymptomatic to sudden cardiac death. Pediatric myocarditis is a rare disease, with an estimated annual incidence of 1 to 2 per 100,000 children though its true prevalence remains unknown due to its variable and often subclinical presentation. The diagnosis of myocarditis is challenging in the era of COVID-19 and Multisystem Inflammatory Syndrome in Children (MIS-C), which can have overlapping clinical conundrum. Here, we present a case of a 17-year-old male presenting with chest tightness, shortness of breath, and electrocardiogram (EKG) findings concerning for myocardial injury along with elevated inflammatory markers such as D-dimer, ESR (Erythrocyte Sedimentation Rate), and CRP (C-Reactive Protein). We discuss the key elements of our clinical experience with this case and review the literature for pediatric myocarditis, with a focus on differentiating it from MIS-C in the current COVID-19 pandemic era. Hindawi 2021-10-04 /pmc/articles/PMC8490073/ /pubmed/34616578 http://dx.doi.org/10.1155/2021/4797498 Text en Copyright © 2021 Hemali P. Shah et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Shah, Hemali P.
Frye, Richard
Chang, Sunny
Faherty, Erin
Steele, Jeremy
Karnik, Ruchika
Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C
title Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C
title_full Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C
title_fullStr Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C
title_full_unstemmed Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C
title_short Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID-19 and MIS-C
title_sort challenges of diagnosing viral myocarditis in adolescents in the era of covid-19 and mis-c
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490073/
https://www.ncbi.nlm.nih.gov/pubmed/34616578
http://dx.doi.org/10.1155/2021/4797498
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