Cargando…
Bioanalytical Challenges due to Prior Checkpoint Inhibitor Exposure: Interference and Mitigation in Drug Concentration and Immunogenicity Assays
Monoclonal antibodies (mAbs) are a leading class of biotherapeutics. In oncology, patients often fail on early lines of biologic therapy to a specific target. Some patients may then enroll in a new clinical trial with a mAb specific for the same target. Therefore, immunoassays designed to quantify t...
Autores principales: | Dengler, Andrew F., Weiss, Rachel, Truong, Tiffany, Irvin, Susan C., Gadhia, Nidhi, Hassanein, Mohamed, Georgaros, Camille, Taylor, Jessica-Ann, Paccaly, Anne, Sumner, Giane, Andisik, Matthew D., Torri, Albert, Partridge, Michael A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490245/ https://www.ncbi.nlm.nih.gov/pubmed/34608545 http://dx.doi.org/10.1208/s12248-021-00643-4 |
Ejemplares similares
-
REGEN-COV(®) antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification
por: Irvin, Susan C, et al.
Publicado: (2021) -
Isotyping and Semi-Quantitation of Monkey Anti-Drug Antibodies by Immunocapture Liquid Chromatography-Mass Spectrometry
por: Huang, Xiaoxiao, et al.
Publicado: (2021) -
Bioanalytical Methods in Toxicology
por: Skrzydlewska, Elżbieta
Publicado: (2008) -
Immunoassay and other bioanalytical techniques /
Publicado: (2007) -
Applications of Lasers in Bioanalytical Chemistry
por: Yeung, Edward S.
Publicado: (1988)