Cargando…

Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?

PURPOSE: Bariatric surgery improves several obesity-related comorbidities. Laryngotracheal stenosis is a rare condition that is usually managed with repeated endoscopic airway interventions and reconstructive airway surgery. The outcome of these definitive operations is worse in individuals with obe...

Descripción completa

Detalles Bibliográficos
Autores principales: Fehervari, Matyas, Patel, Shivali, Towning, Rebecca, Haire, Kevin, Al Yaghchi, Chadwan, Sabharwal, Atika, Sandhu, Guri, Efthimiou, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490261/
https://www.ncbi.nlm.nih.gov/pubmed/34389931
http://dx.doi.org/10.1007/s11695-021-05647-9
_version_ 1784578495597248512
author Fehervari, Matyas
Patel, Shivali
Towning, Rebecca
Haire, Kevin
Al Yaghchi, Chadwan
Sabharwal, Atika
Sandhu, Guri
Efthimiou, Evangelos
author_facet Fehervari, Matyas
Patel, Shivali
Towning, Rebecca
Haire, Kevin
Al Yaghchi, Chadwan
Sabharwal, Atika
Sandhu, Guri
Efthimiou, Evangelos
author_sort Fehervari, Matyas
collection PubMed
description PURPOSE: Bariatric surgery improves several obesity-related comorbidities. Laryngotracheal stenosis is a rare condition that is usually managed with repeated endoscopic airway interventions and reconstructive airway surgery. The outcome of these definitive operations is worse in individuals with obesity. There are no studies investigating the effect of weight loss following bariatric surgery in the management of laryngotracheal stenosis. MATERIALS AND METHODS: In an observational study, consecutive patients with a BMI over 35 kg/m(2) and laryngotracheal stenosis were prospectively recruited to a bariatric and airway stenosis database in two tertiary care centres. Patients were treated with laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy and control subjects were managed conservatively. RESULTS: A total of eleven patients with an initial body mass index of 43 kg/m(2) (37–45) were enrolled to this study. Six patients underwent bariatric surgery and five subjects were treated conservatively. After 12 months, the total weight loss of patients undergoing bariatric surgery was 19.4% (14–24%) whilst 2.3% (1–3%) in the control group. The annual number of endoscopic airway interventions following bariatric surgery reduced (p = 0.002). Higher weight loss in patients led to less frequent interventions compared to control subjects (p = 0.004). Patients undergoing laryngotracheal reconstruction following bariatric surgery needed less endoscopic intervention, an annual average of 1.9 interventions before vs 0.5 intervention after. Conservatively managed control subjects required more frequent endoscopic intervention, 1.8 before vs 3.4 after airway reconstruction. CONCLUSION: Bariatric surgery reduced the number of endoscopic airway interventions and enabled patients to undergo successful definitive airway reconstructive surgery.
format Online
Article
Text
id pubmed-8490261
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-84902612021-10-15 Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery? Fehervari, Matyas Patel, Shivali Towning, Rebecca Haire, Kevin Al Yaghchi, Chadwan Sabharwal, Atika Sandhu, Guri Efthimiou, Evangelos Obes Surg Original Contributions PURPOSE: Bariatric surgery improves several obesity-related comorbidities. Laryngotracheal stenosis is a rare condition that is usually managed with repeated endoscopic airway interventions and reconstructive airway surgery. The outcome of these definitive operations is worse in individuals with obesity. There are no studies investigating the effect of weight loss following bariatric surgery in the management of laryngotracheal stenosis. MATERIALS AND METHODS: In an observational study, consecutive patients with a BMI over 35 kg/m(2) and laryngotracheal stenosis were prospectively recruited to a bariatric and airway stenosis database in two tertiary care centres. Patients were treated with laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy and control subjects were managed conservatively. RESULTS: A total of eleven patients with an initial body mass index of 43 kg/m(2) (37–45) were enrolled to this study. Six patients underwent bariatric surgery and five subjects were treated conservatively. After 12 months, the total weight loss of patients undergoing bariatric surgery was 19.4% (14–24%) whilst 2.3% (1–3%) in the control group. The annual number of endoscopic airway interventions following bariatric surgery reduced (p = 0.002). Higher weight loss in patients led to less frequent interventions compared to control subjects (p = 0.004). Patients undergoing laryngotracheal reconstruction following bariatric surgery needed less endoscopic intervention, an annual average of 1.9 interventions before vs 0.5 intervention after. Conservatively managed control subjects required more frequent endoscopic intervention, 1.8 before vs 3.4 after airway reconstruction. CONCLUSION: Bariatric surgery reduced the number of endoscopic airway interventions and enabled patients to undergo successful definitive airway reconstructive surgery. Springer US 2021-08-14 2021 /pmc/articles/PMC8490261/ /pubmed/34389931 http://dx.doi.org/10.1007/s11695-021-05647-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Contributions
Fehervari, Matyas
Patel, Shivali
Towning, Rebecca
Haire, Kevin
Al Yaghchi, Chadwan
Sabharwal, Atika
Sandhu, Guri
Efthimiou, Evangelos
Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?
title Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?
title_full Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?
title_fullStr Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?
title_full_unstemmed Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?
title_short Management of Laryngotracheal Stenosis in Obesity. Is This Another Co-morbidity that Can Be Improved with Weight Loss Following Bariatric Surgery?
title_sort management of laryngotracheal stenosis in obesity. is this another co-morbidity that can be improved with weight loss following bariatric surgery?
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490261/
https://www.ncbi.nlm.nih.gov/pubmed/34389931
http://dx.doi.org/10.1007/s11695-021-05647-9
work_keys_str_mv AT fehervarimatyas managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT patelshivali managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT towningrebecca managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT hairekevin managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT alyaghchichadwan managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT sabharwalatika managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT sandhuguri managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery
AT efthimiouevangelos managementoflaryngotrachealstenosisinobesityisthisanothercomorbiditythatcanbeimprovedwithweightlossfollowingbariatricsurgery