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Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach
Elevated serum uric acid (SUA)—hyperuricemia—is caused by overproduction of urate or by its decreased renal and/or intestinal excretion. This disease, which is increasing in prevalence worldwide, is associated with both gout and metabolic diseases. Several studies have reported relationships between...
Autores principales: | Ogura, Masatsune, Toyoda, Yu, Sakiyama, Masayuki, Kawamura, Yusuke, Nakayama, Akiyoshi, Yamanashi, Yoshihide, Takada, Tappei, Shimizu, Seiko, Higashino, Toshihide, Nakajima, Mayuko, Naito, Mariko, Hishida, Asahi, Kawai, Sayo, Okada, Rieko, Sasaki, Makoto, Ayaori, Makoto, Suzuki, Hiroshi, Takata, Koki, Ikewaki, Katsunori, Harada-Shiba, Mariko, Shinomiya, Nariyoshi, Matsuo, Hirotaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490264/ https://www.ncbi.nlm.nih.gov/pubmed/34532841 http://dx.doi.org/10.1007/s13577-021-00609-w |
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