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Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach

Elevated serum uric acid (SUA)—hyperuricemia—is caused by overproduction of urate or by its decreased renal and/or intestinal excretion. This disease, which is increasing in prevalence worldwide, is associated with both gout and metabolic diseases. Several studies have reported relationships between...

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Detalles Bibliográficos
Autores principales: Ogura, Masatsune, Toyoda, Yu, Sakiyama, Masayuki, Kawamura, Yusuke, Nakayama, Akiyoshi, Yamanashi, Yoshihide, Takada, Tappei, Shimizu, Seiko, Higashino, Toshihide, Nakajima, Mayuko, Naito, Mariko, Hishida, Asahi, Kawai, Sayo, Okada, Rieko, Sasaki, Makoto, Ayaori, Makoto, Suzuki, Hiroshi, Takata, Koki, Ikewaki, Katsunori, Harada-Shiba, Mariko, Shinomiya, Nariyoshi, Matsuo, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490264/
https://www.ncbi.nlm.nih.gov/pubmed/34532841
http://dx.doi.org/10.1007/s13577-021-00609-w

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