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Protein identification by nanopore peptide profiling

Nanopores are single-molecule sensors used in nucleic acid analysis, whereas their applicability towards full protein identification has yet to be demonstrated. Here, we show that an engineered Fragaceatoxin C nanopore is capable of identifying individual proteins by measuring peptide spectra that a...

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Detalles Bibliográficos
Autores principales: Lucas, Florian Leonardus Rudolfus, Versloot, Roderick Corstiaan Abraham, Yakovlieva, Liubov, Walvoort, Marthe T. C., Maglia, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490355/
https://www.ncbi.nlm.nih.gov/pubmed/34608150
http://dx.doi.org/10.1038/s41467-021-26046-9