Cargando…

Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection

SARS-CoV-2 has caused a global pandemic of COVID-19 since its emergence in December 2019. The infection causes a severe acute respiratory syndrome and may also spread to central nervous system leading to neurological sequelae. We have developed and characterized two new organotypic cultures from ham...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferren, Marion, Favède, Valérie, Decimo, Didier, Iampietro, Mathieu, Lieberman, Nicole A. P., Weickert, Jean-Luc, Pelissier, Rodolphe, Mazelier, Magalie, Terrier, Olivier, Moscona, Anne, Porotto, Matteo, Greninger, Alexander L., Messaddeq, Nadia, Horvat, Branka, Mathieu, Cyrille
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490365/ https://www.ncbi.nlm.nih.gov/pubmed/34608167 http://dx.doi.org/10.1038/s41467-021-26096-z

Ejemplares similares

Hamster organotypic kidney culture model of early-stage SARS-CoV-2 infection highlights a two-step renal susceptibility
por: Shyfrin, Sophie R, et al.
Publicado: (2022)

Recent advances in the understanding of Nipah virus immunopathogenesis and anti-viral approaches
por: Pelissier, Rodolphe, et al.
Publicado: (2019)

Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure
por: Ferren, Marion, et al.
Publicado: (2023)

Fusion Inhibitory Lipopeptides Engineered for Prophylaxis of Nipah Virus in Primates
por: Mathieu, Cyrille, et al.
Publicado: (2018)

Measles Encephalitis: Towards New Therapeutics
por: Ferren, Marion, et al.
Publicado: (2019)

Activation of cGAS/STING pathway upon paramyxovirus infection
por: Iampietro, Mathieu, et al.
Publicado: (2021)

Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection
por: Reynard, Olivier, et al.
Publicado: (2022)

Measles Fusion Machinery Is Dysregulated in Neuropathogenic Variants
por: Jurgens, Eric M., et al.
Publicado: (2015)

Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response
por: Enchéry, François, et al.
Publicado: (2021)

Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection
por: Reynard, Olivier, et al.
Publicado: (2022)

Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain
por: Mathieu, Cyrille, et al.
Publicado: (2021)

Viral Entry Properties Required for Fitness in Humans Are Lost through Rapid Genomic Change during Viral Isolation
por: Iketani, Sho, et al.
Publicado: (2018)

Rapid Screening for Entry Inhibitors of Highly Pathogenic Viruses under Low-Level Biocontainment
por: Talekar, Aparna, et al.
Publicado: (2012)

Interplay between RNA viruses and cGAS/STING axis in innate immunity
por: Amurri, Lucia, et al.
Publicado: (2023)

A General Strategy to Endow Natural Fusion-protein-Derived Peptides with Potent Antiviral Activity
por: Pessi, Antonello, et al.
Publicado: (2012)

Measles Virus-Induced Host Immunity and Mechanisms of Viral Evasion
por: Amurri, Lucia, et al.
Publicado: (2022)

A Bioluminescent 3CL(Pro) Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors
por: Mathieu, Cyrille, et al.
Publicado: (2021)

Rapid and Flexible Platform To Assess Anti-SARS-CoV-2 Antibody Neutralization and Spike Protein-Specific Antivirals
por: Stelitano, Debora, et al.
Publicado: (2021)

Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides
por: Mathieu, Cyrille, et al.
Publicado: (2017)

Authentic Modeling of Human Respiratory Virus Infection in Human Pluripotent Stem Cell-Derived Lung Organoids
por: Porotto, M., et al.
Publicado: (2019)

Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures
por: Busceti, Carla L., et al.
Publicado: (2019)

High Pathogenicity of Nipah Virus from Pteropus lylei Fruit Bats, Cambodia
por: Gaudino, Maria, et al.
Publicado: (2020)

CO(2)-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture
por: Forsberg, David, et al.
Publicado: (2016)

SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients
por: Charvet, Benjamin, et al.
Publicado: (2023)

Non-Productive Infection of Glial Cells with SARS-CoV-2 in Hamster Organotypic Cerebellar Slice Cultures
por: Lamoureux, Lise, et al.
Publicado: (2022)

Lethal Nipah Virus Infection Induces Rapid Overexpression of CXCL10
por: Mathieu, Cyrille, et al.
Publicado: (2012)

Synthetic Protocells Interact with Viral Nanomachinery and Inactivate Pathogenic Human Virus
por: Porotto, Matteo, et al.
Publicado: (2011)

Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length
por: Augusto, Marcelo T., et al.
Publicado: (2017)

Disabling of lymphocyte immune response by Ebola virus
por: Younan, Patrick, et al.
Publicado: (2018)

Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces
por: Marcink, Tara C., et al.
Publicado: (2020)

Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy
por: Marcink, T. C., et al.
Publicado: (2020)

STLV-1 Commonly Targets Neurons in the Brain of Asymptomatic Non-Human Primates
por: Rocamonde, Brenda, et al.
Publicado: (2023)

Uukuniemi Virus as a Tick-Borne Virus Model
por: Mazelier, Magalie, et al.
Publicado: (2016)

In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age
por: Lieberman, Nicole A. P., et al.
Publicado: (2020)

Heparan Sulfate-Dependent Enhancement of Henipavirus Infection
por: Mathieu, Cyrille, et al.
Publicado: (2015)

Erratum for Gui et al., Electron Tomography Imaging of Surface Glycoproteins on Human Parainfluenza Virus 3: Association of Receptor Binding and Fusion Proteins before Receptor Engagement
por: Gui, Long, et al.
Publicado: (2016)

Host Cell Membrane Capture by the SARS-CoV-2 Spike Protein Fusion Intermediate
por: Su, Rui, et al.
Publicado: (2023)

Inhibiting Human Parainfluenza Virus Infection by Preactivating the Cell Entry Mechanism
por: Bottom-Tanzer, S. F., et al.
Publicado: (2019)

Organotypic Modeling of the Tumor Landscape
por: Haykal, Maria M., et al.
Publicado: (2020)

Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms
por: Marcink, Tara C., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1lvtskechllgmn54mhc0ukug5n