TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG

Background: Neuronal death is a major hallmark of Alzheimer's disease (AD). Necroptosis, as a programmed necrotic process, is activated in AD. However, what signals and factors initiate necroptosis in AD is largely unknown. Methods: We examined the expression levels of critical molecules in nec...

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Detalles Bibliográficos
Autores principales: Xu, Chong, Wu, Jialin, Wu, Yiqun, Ren, Zhichu, Yao, Yuyuan, Chen, Guobing, Fang, Evandro F., Noh, Ji Heon, Liu, Yong U., Wei, Libin, Chen, Xijing, Sima, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490500/
https://www.ncbi.nlm.nih.gov/pubmed/34646380
http://dx.doi.org/10.7150/thno.62376

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