Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma

Tryptophan (Trp)-catabolic enzymes (TCEs) produce metabolites that activate the aryl hydrocarbon receptor (AHR) and promote tumor progression and immunosuppression in glioblastoma. As therapies targeting TCEs or AHR become available, a better understanding of Trp metabolism is required. Methods: The...

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Detalles Bibliográficos
Autores principales: Panitz, Verena, Končarević, Saša, Sadik, Ahmed, Friedel, Dennis, Bausbacher, Tobias, Trump, Saskia, Farztdinov, Vadim, Schulz, Sandra, Sievers, Philipp, Schmidt, Stefan, Jürgenson, Ina, Jung, Stephan, Kuhn, Karsten, Pflüger, Irada, Sharma, Suraj, Wick, Antje, Pfänder, Pauline, Selzer, Stefan, Vollmuth, Philipp, Sahm, Felix, von Deimling, Andreas, Heiland, Ines, Hopf, Carsten, Schulz-Knappe, Peter, Pike, Ian, Platten, Michael, Wick, Wolfgang, Opitz, Christiane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490504/
https://www.ncbi.nlm.nih.gov/pubmed/34646367
http://dx.doi.org/10.7150/thno.60679

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