Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells

Rationale: Recurrent and metastatic cancers often undergo a period of dormancy, which is closely associated with cellular quiescence, a state whereby cells exit the cell cycle and are reversibly arrested in G0 phase. Curative cancer treatment thus requires therapies that either sustain the dormant s...

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Detalles Bibliográficos
Autores principales: La, Ting, Chen, Song, Guo, Tao, Zhao, Xiao Hong, Teng, Liu, Li, Dandan, Carnell, Michael, Zhang, Yuan Yuan, Feng, Yu Chen, Cole, Nicole, Brown, Alexandra C., Zhang, Didi, Dong, Qihan, Wang, Jenny Y., Cao, Huixia, Liu, Tao, Thorne, Rick F., Shao, Feng-Min, Zhang, Xu Dong, Jin, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490506/
https://www.ncbi.nlm.nih.gov/pubmed/34646389
http://dx.doi.org/10.7150/thno.63763

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