BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators

Cell cycle regulators are frequently altered in Triple-Negative Breast Cancer (TNBC). Emerging agents targeting these signals offer the possibility to design new combinatorial therapies. However, preclinical models that recapitulate TNBC primary resistance and heterogeneity are essential to evaluate...

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Detalles Bibliográficos
Autores principales: Castellanet, Olivier, Ahmad, Fahmida, Vinik, Yaron, Mills, Gordon B., Habermann, Bianca, Borg, Jean-Paul, Lev, Sima, Lamballe, Fabienne, Maina, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490507/
https://www.ncbi.nlm.nih.gov/pubmed/34646365
http://dx.doi.org/10.7150/thno.60503

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