Interruption of neutrophil extracellular traps formation dictates host defense and tubular HOXA5 stability to augment efficacy of anti-Fn14 therapy against septic AKI

The immunosuppressive, inflammatory microenvironment orchestrated by neutrophil extracellular traps (NETs) plays a principal role in pathogenesis of sepsis. Fibroblast growth factor-inducible molecule 14 (Fn14) has been established as a potential target for septic acute kidney injury (AKI), making f...

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Detalles Bibliográficos
Autores principales: Ni, Yin, Hu, Bang-Chuan, Wu, Guo-Hua, Shao, Zi-Qiang, Zheng, Yang, Zhang, Run, Jin, Jun, Hong, Jun, Yang, Xiang-Hong, Sun, Ren-Hua, Liu, Jin-Quan, Mo, Shi-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490525/
https://www.ncbi.nlm.nih.gov/pubmed/34646379
http://dx.doi.org/10.7150/thno.61902

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