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The Exosomal lncRNA KLF3-AS1 From Ischemic Cardiomyocytes Mediates IGF-1 Secretion by MSCs to Rescue Myocardial Ischemia-Reperfusion Injury

The purpose of the study was to explore the mechanism by which myocardial ischemia-reperfusion (I/R) injury-induced exosomes modulate mesenchymal stem cells (MSCs) to regulate myocardial injury. In this study, we established an I/R injury model in vivo and a hypoxia-reoxygenation (H/R) model in vitr...

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Detalles Bibliográficos
Autores principales: Chen, Gecai, Yue, Aihuan, Wang, Meixiang, Ruan, Zhongbao, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490635/
https://www.ncbi.nlm.nih.gov/pubmed/34621793
http://dx.doi.org/10.3389/fcvm.2021.671610

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