Cargando…

Spironolactone Attenuates Methylglyoxal-induced Cellular Dysfunction in MC3T3-E1 Osteoblastic Cells

BACKGROUND: Methylglyoxal (MG) is associated with the pathogenesis of age- and diabetes-related complications. Spironolactone is a competitive antagonist of aldosterone that is widely employed in the treatment of hypertension and heart failure. This study examined the effects of spironolactone on MG...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, So Young, Suh, Kwang Sik, Jung, Woon-Won, Chin, Sang Ouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490790/
https://www.ncbi.nlm.nih.gov/pubmed/34609092
http://dx.doi.org/10.3346/jkms.2021.36.e265