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AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs

According to the World Health Organization (WHO), novel coronavirus (COVID-19) is an infectious disease and has a significant social and economic impact. The main challenge in fighting against this disease is its scale. Due to the outbreak, medical facilities are under pressure due to case numbers....

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Autores principales: Arora, Ridhi, Bansal, Vipul, Buckchash, Himanshu, Kumar, Rahul, Sahayasheela, Vinodh J., Narayanan, Narayanan, Pandian, Ganesh N., Raman, Balasubramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490848/
https://www.ncbi.nlm.nih.gov/pubmed/34609703
http://dx.doi.org/10.1007/s13246-021-01060-9
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author Arora, Ridhi
Bansal, Vipul
Buckchash, Himanshu
Kumar, Rahul
Sahayasheela, Vinodh J.
Narayanan, Narayanan
Pandian, Ganesh N.
Raman, Balasubramanian
author_facet Arora, Ridhi
Bansal, Vipul
Buckchash, Himanshu
Kumar, Rahul
Sahayasheela, Vinodh J.
Narayanan, Narayanan
Pandian, Ganesh N.
Raman, Balasubramanian
author_sort Arora, Ridhi
collection PubMed
description According to the World Health Organization (WHO), novel coronavirus (COVID-19) is an infectious disease and has a significant social and economic impact. The main challenge in fighting against this disease is its scale. Due to the outbreak, medical facilities are under pressure due to case numbers. A quick diagnosis system is required to address these challenges. To this end, a stochastic deep learning model is proposed. The main idea is to constrain the deep-representations over a Gaussian prior to reinforce the discriminability in feature space. The model can work on chest X-ray or CT-scan images. It provides a fast diagnosis of COVID-19 and can scale seamlessly. The work presents a comprehensive evaluation of previously proposed approaches for X-ray based disease diagnosis. The approach works by learning a latent space over X-ray image distribution from the ensemble of state-of-the-art convolutional-nets, and then linearly regressing the predictions from an ensemble of classifiers which take the latent vector as input. We experimented with publicly available datasets having three classes: COVID-19, normal and pneumonia yielding an overall accuracy and AUC of 0.91 and 0.97, respectively. Moreover, for robust evaluation, experiments were performed on a large chest X-ray dataset to classify among Atelectasis, Effusion, Infiltration, Nodule, and Pneumonia classes. The results demonstrate that the proposed model has better understanding of the X-ray images which make the network more generic to be later used with other domains of medical image analysis.
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spelling pubmed-84908482021-10-05 AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs Arora, Ridhi Bansal, Vipul Buckchash, Himanshu Kumar, Rahul Sahayasheela, Vinodh J. Narayanan, Narayanan Pandian, Ganesh N. Raman, Balasubramanian Phys Eng Sci Med Scientific Paper According to the World Health Organization (WHO), novel coronavirus (COVID-19) is an infectious disease and has a significant social and economic impact. The main challenge in fighting against this disease is its scale. Due to the outbreak, medical facilities are under pressure due to case numbers. A quick diagnosis system is required to address these challenges. To this end, a stochastic deep learning model is proposed. The main idea is to constrain the deep-representations over a Gaussian prior to reinforce the discriminability in feature space. The model can work on chest X-ray or CT-scan images. It provides a fast diagnosis of COVID-19 and can scale seamlessly. The work presents a comprehensive evaluation of previously proposed approaches for X-ray based disease diagnosis. The approach works by learning a latent space over X-ray image distribution from the ensemble of state-of-the-art convolutional-nets, and then linearly regressing the predictions from an ensemble of classifiers which take the latent vector as input. We experimented with publicly available datasets having three classes: COVID-19, normal and pneumonia yielding an overall accuracy and AUC of 0.91 and 0.97, respectively. Moreover, for robust evaluation, experiments were performed on a large chest X-ray dataset to classify among Atelectasis, Effusion, Infiltration, Nodule, and Pneumonia classes. The results demonstrate that the proposed model has better understanding of the X-ray images which make the network more generic to be later used with other domains of medical image analysis. Springer International Publishing 2021-10-05 2021 /pmc/articles/PMC8490848/ /pubmed/34609703 http://dx.doi.org/10.1007/s13246-021-01060-9 Text en © Australasian College of Physical Scientists and Engineers in Medicine 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Scientific Paper
Arora, Ridhi
Bansal, Vipul
Buckchash, Himanshu
Kumar, Rahul
Sahayasheela, Vinodh J.
Narayanan, Narayanan
Pandian, Ganesh N.
Raman, Balasubramanian
AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
title AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
title_full AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
title_fullStr AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
title_full_unstemmed AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
title_short AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
title_sort ai-based diagnosis of covid-19 patients using x-ray scans with stochastic ensemble of cnns
topic Scientific Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490848/
https://www.ncbi.nlm.nih.gov/pubmed/34609703
http://dx.doi.org/10.1007/s13246-021-01060-9
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