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AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs
According to the World Health Organization (WHO), novel coronavirus (COVID-19) is an infectious disease and has a significant social and economic impact. The main challenge in fighting against this disease is its scale. Due to the outbreak, medical facilities are under pressure due to case numbers....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490848/ https://www.ncbi.nlm.nih.gov/pubmed/34609703 http://dx.doi.org/10.1007/s13246-021-01060-9 |
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author | Arora, Ridhi Bansal, Vipul Buckchash, Himanshu Kumar, Rahul Sahayasheela, Vinodh J. Narayanan, Narayanan Pandian, Ganesh N. Raman, Balasubramanian |
author_facet | Arora, Ridhi Bansal, Vipul Buckchash, Himanshu Kumar, Rahul Sahayasheela, Vinodh J. Narayanan, Narayanan Pandian, Ganesh N. Raman, Balasubramanian |
author_sort | Arora, Ridhi |
collection | PubMed |
description | According to the World Health Organization (WHO), novel coronavirus (COVID-19) is an infectious disease and has a significant social and economic impact. The main challenge in fighting against this disease is its scale. Due to the outbreak, medical facilities are under pressure due to case numbers. A quick diagnosis system is required to address these challenges. To this end, a stochastic deep learning model is proposed. The main idea is to constrain the deep-representations over a Gaussian prior to reinforce the discriminability in feature space. The model can work on chest X-ray or CT-scan images. It provides a fast diagnosis of COVID-19 and can scale seamlessly. The work presents a comprehensive evaluation of previously proposed approaches for X-ray based disease diagnosis. The approach works by learning a latent space over X-ray image distribution from the ensemble of state-of-the-art convolutional-nets, and then linearly regressing the predictions from an ensemble of classifiers which take the latent vector as input. We experimented with publicly available datasets having three classes: COVID-19, normal and pneumonia yielding an overall accuracy and AUC of 0.91 and 0.97, respectively. Moreover, for robust evaluation, experiments were performed on a large chest X-ray dataset to classify among Atelectasis, Effusion, Infiltration, Nodule, and Pneumonia classes. The results demonstrate that the proposed model has better understanding of the X-ray images which make the network more generic to be later used with other domains of medical image analysis. |
format | Online Article Text |
id | pubmed-8490848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-84908482021-10-05 AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs Arora, Ridhi Bansal, Vipul Buckchash, Himanshu Kumar, Rahul Sahayasheela, Vinodh J. Narayanan, Narayanan Pandian, Ganesh N. Raman, Balasubramanian Phys Eng Sci Med Scientific Paper According to the World Health Organization (WHO), novel coronavirus (COVID-19) is an infectious disease and has a significant social and economic impact. The main challenge in fighting against this disease is its scale. Due to the outbreak, medical facilities are under pressure due to case numbers. A quick diagnosis system is required to address these challenges. To this end, a stochastic deep learning model is proposed. The main idea is to constrain the deep-representations over a Gaussian prior to reinforce the discriminability in feature space. The model can work on chest X-ray or CT-scan images. It provides a fast diagnosis of COVID-19 and can scale seamlessly. The work presents a comprehensive evaluation of previously proposed approaches for X-ray based disease diagnosis. The approach works by learning a latent space over X-ray image distribution from the ensemble of state-of-the-art convolutional-nets, and then linearly regressing the predictions from an ensemble of classifiers which take the latent vector as input. We experimented with publicly available datasets having three classes: COVID-19, normal and pneumonia yielding an overall accuracy and AUC of 0.91 and 0.97, respectively. Moreover, for robust evaluation, experiments were performed on a large chest X-ray dataset to classify among Atelectasis, Effusion, Infiltration, Nodule, and Pneumonia classes. The results demonstrate that the proposed model has better understanding of the X-ray images which make the network more generic to be later used with other domains of medical image analysis. Springer International Publishing 2021-10-05 2021 /pmc/articles/PMC8490848/ /pubmed/34609703 http://dx.doi.org/10.1007/s13246-021-01060-9 Text en © Australasian College of Physical Scientists and Engineers in Medicine 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Scientific Paper Arora, Ridhi Bansal, Vipul Buckchash, Himanshu Kumar, Rahul Sahayasheela, Vinodh J. Narayanan, Narayanan Pandian, Ganesh N. Raman, Balasubramanian AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs |
title | AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs |
title_full | AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs |
title_fullStr | AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs |
title_full_unstemmed | AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs |
title_short | AI-based diagnosis of COVID-19 patients using X-ray scans with stochastic ensemble of CNNs |
title_sort | ai-based diagnosis of covid-19 patients using x-ray scans with stochastic ensemble of cnns |
topic | Scientific Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490848/ https://www.ncbi.nlm.nih.gov/pubmed/34609703 http://dx.doi.org/10.1007/s13246-021-01060-9 |
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