Cargando…
BRD9 is a druggable component of interferon‐stimulated gene expression and antiviral activity
Interferon (IFN) induction of IFN‐stimulated genes (ISGs) creates a formidable protective antiviral state. However, loss of appropriate control mechanisms can result in constitutive pathogenic ISG upregulation. Here, we used genome‐scale loss‐of‐function screening to establish genes critical for IFN...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490982/ https://www.ncbi.nlm.nih.gov/pubmed/34397140 http://dx.doi.org/10.15252/embr.202152823 |