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Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere

Striated muscle undergoes remodelling in response to mechanical and physiological stress, but little is known about the integration of such varied signals in the myofibril. The interaction of the elastic kinase region from sarcomeric titin (A168‐M1) with the autophagy receptors Nbr1/p62 and MuRF E3...

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Detalles Bibliográficos
Autores principales: Bogomolovas, Julius, Fleming, Jennifer R, Franke, Barbara, Manso, Bruno, Simon, Bernd, Gasch, Alexander, Markovic, Marija, Brunner, Thomas, Knöll, Ralph, Chen, Ju, Labeit, Siegfried, Scheffner, Martin, Peter, Christine, Mayans, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490993/
https://www.ncbi.nlm.nih.gov/pubmed/34402565
http://dx.doi.org/10.15252/embr.201948018

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