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Catalytic Diastereo- and Enantioselective Vinylogous Mannich Reaction of Alkylidenepyrazolones to Isatin-Derived Ketimines

[Image: see text] A valuable organocatalytic vinylogous Mannich reaction between alkylidenepyrazolones and isatin-derived ketimines has been successfully established. Squaramide organocatalyst, prepared from quinine, catalyzed the diastereo- and enantioselective vinylogous Mannich addition, affordin...

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Detalles Bibliográficos
Autores principales: Carceller-Ferrer, Laura, Vila, Carlos, Blay, Gonzalo, Muñoz, M. Carmen, Pedro, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491163/
https://www.ncbi.nlm.nih.gov/pubmed/34553948
http://dx.doi.org/10.1021/acs.orglett.1c02571

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