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Modelling t(8;21) acute myeloid leukaemia ‐ What have we learned?

Acute myeloid leukaemia (AML) is a heterogeneous haematopoietic malignancy caused by recurrent mutations in haematopoietic stem and progenitor cells that affect both the epigenetic regulatory machinery and signalling molecules. The t(8;21) or RUNX1‐RUNX1T1 translocation generates the RUNX1‐ETO chime...

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Detalles Bibliográficos
Autores principales:	Chin, Paulynn Suyin, Bonifer, Constanze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491201/ https://www.ncbi.nlm.nih.gov/pubmed/34766123 http://dx.doi.org/10.1002/mco2.30

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