Assessment of Uncertainty Depending on Various Conditions in Modulation Transfer Function Calculation Using the Edge Method

In medical X-ray imaging, to perform optimal operations, it is essential for the user to understand whether a required image quality level which depends on a diagnostic task can be achieved with the imaging system used. This study focuses on the effects of noise on the modulation transfer function (MTF) using the edge method, the most widely used to evaluate the task dependence property. The purpose is to verify the uncertainty of the MTF value at each spatial frequency and examine the conditions under which the accuracy is ensured. By using a Monte Carlo simulation, edge images with various contrast-to-noise ratio (CNR) are acquired. MTFs are then calculated with different edge spread function (ESF) lengths. The uncertainties for each spatial frequency are estimated based on the independent MTF calculations obtained from the five edge data. The uncertainty of the MTF is inversely proportional to the CNR. In the frequency range up to the Nyquist frequency, the uncertainty in five calculations is <0.01 when the CNR is more than 60. In addition, it is observed that the uncertainty increases as the ESF length increases. This relationship depends on the frequency range, but it is proportional to the 0.3–0.5 power of the ESF length. The results in which the uncertainty is most likely to be large in the MTF calculation are clearly shown. Therefore, it is expected to provide an important barometer and useful insights for a proper image quality measurement.