Influenza a virus NS1 resembles a TRAF3-interacting motif to target the RNA sensing-TRAF3-type I IFN axis and impair antiviral innate immunity

BACKGROUND: Influenza A virus (IAV) evolves strategies to counteract the host antiviral defense for establishing infection. The influenza A virus (IAV) non-structural protein 1 (NS1) is a key viral factor shown to counteract type I IFN antiviral response mainly through targeting RIG-I signaling. Gro...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Yang, Shih, Meng-Cen, Chang, Hung-Chun, Lin, Kuan-Jung, Chen, Lin-Fang, Huang, Sheng-Wen, Yang, Mei-Lin, Ma, Sheng-Kai, Shiau, Ai-Li, Wang, Jen-Ren, Chen, Kuan-Ru, Ling, Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491413/
https://www.ncbi.nlm.nih.gov/pubmed/34610835
http://dx.doi.org/10.1186/s12929-021-00764-0

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