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Multiplex Biosensing for Simultaneous Detection of Mutations in SARS-CoV-2
[Image: see text] COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has become the world’s largest public health emergency of the past few decades. Thousands of mutations were identified in the SARS-CoV-2 genome. Some mutants are more infectious and ma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491437/ https://www.ncbi.nlm.nih.gov/pubmed/34632242 http://dx.doi.org/10.1021/acsomega.1c04024 |
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author | Xi, Hui Jiang, Hanlin Juhas, Mario Zhang, Yang |
author_facet | Xi, Hui Jiang, Hanlin Juhas, Mario Zhang, Yang |
author_sort | Xi, Hui |
collection | PubMed |
description | [Image: see text] COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has become the world’s largest public health emergency of the past few decades. Thousands of mutations were identified in the SARS-CoV-2 genome. Some mutants are more infectious and may replace the original strains. Recently, B.1.1.7(Alpha), B1.351(Beta), and B.1.617.2(Delta) strains, which appear to have increased transmissibility, were detected. These strains accounting for the high proportion of newly diagnosed cases spread rapidly over the world. Particularly, the Delta variant has been reported to account for a vast majority of the infections in several countries over the last few weeks. The application of biosensors in the detection of SARS-CoV-2 is important for the control of the COVID-19 pandemic. Due to high demand for SARS-CoV-2 genotyping, it is urgent to develop reliable and efficient systems based on integrated multiple biosensor technology for rapid detection of multiple SARS-CoV-2 mutations simultaneously. This is important not only for the detection and analysis of the current but also for future mutations. Novel biosensors combined with other technologies can be used for the reliable and effective detection of SARS-CoV-2 mutants. |
format | Online Article Text |
id | pubmed-8491437 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-84914372021-10-05 Multiplex Biosensing for Simultaneous Detection of Mutations in SARS-CoV-2 Xi, Hui Jiang, Hanlin Juhas, Mario Zhang, Yang ACS Omega [Image: see text] COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has become the world’s largest public health emergency of the past few decades. Thousands of mutations were identified in the SARS-CoV-2 genome. Some mutants are more infectious and may replace the original strains. Recently, B.1.1.7(Alpha), B1.351(Beta), and B.1.617.2(Delta) strains, which appear to have increased transmissibility, were detected. These strains accounting for the high proportion of newly diagnosed cases spread rapidly over the world. Particularly, the Delta variant has been reported to account for a vast majority of the infections in several countries over the last few weeks. The application of biosensors in the detection of SARS-CoV-2 is important for the control of the COVID-19 pandemic. Due to high demand for SARS-CoV-2 genotyping, it is urgent to develop reliable and efficient systems based on integrated multiple biosensor technology for rapid detection of multiple SARS-CoV-2 mutations simultaneously. This is important not only for the detection and analysis of the current but also for future mutations. Novel biosensors combined with other technologies can be used for the reliable and effective detection of SARS-CoV-2 mutants. American Chemical Society 2021-09-28 /pmc/articles/PMC8491437/ /pubmed/34632242 http://dx.doi.org/10.1021/acsomega.1c04024 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Xi, Hui Jiang, Hanlin Juhas, Mario Zhang, Yang Multiplex Biosensing for Simultaneous Detection of Mutations in SARS-CoV-2 |
title | Multiplex Biosensing for Simultaneous Detection of
Mutations in SARS-CoV-2 |
title_full | Multiplex Biosensing for Simultaneous Detection of
Mutations in SARS-CoV-2 |
title_fullStr | Multiplex Biosensing for Simultaneous Detection of
Mutations in SARS-CoV-2 |
title_full_unstemmed | Multiplex Biosensing for Simultaneous Detection of
Mutations in SARS-CoV-2 |
title_short | Multiplex Biosensing for Simultaneous Detection of
Mutations in SARS-CoV-2 |
title_sort | multiplex biosensing for simultaneous detection of
mutations in sars-cov-2 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491437/ https://www.ncbi.nlm.nih.gov/pubmed/34632242 http://dx.doi.org/10.1021/acsomega.1c04024 |
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