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Pro-resolving lipid mediator lipoxin A(4) attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome

The chronic neuro-inflammatory character of multiple sclerosis (MS) suggests that the natural process to resolve inflammation is impaired. This protective process is orchestrated by specialized pro-resolving lipid mediators (SPMs), but to date, the role of SPMs in MS remains largely unknown. Here, w...

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Detalles Bibliográficos
Autores principales: Troletti, Claudio Derada, Enzmann, Gaby, Chiurchiù, Valerio, Kamermans, Alwin, Tietz, Silvia Martina, Norris, Paul C., Jahromi, Neda Haghayegh, Leuti, Alessandro, van der Pol, Susanne M.A., Schouten, Marijn, Serhan, Charles N., de Vries, Helga E., Engelhardt, Britta, Kooij, Gijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8491454/
https://www.ncbi.nlm.nih.gov/pubmed/34077725
http://dx.doi.org/10.1016/j.celrep.2021.109201